Literature summary for 5.3.3.B2 extracted from

Liavonchanka, A.; Hornung, E.; Feussner, I.; Rudolph, M.G.
Structure and mechanism of the Propionibacterium acnes polyunsaturated fatty acid isomerase (2006), Proc. Natl. Acad. Sci. USA, 103, 2576-2581.

Search for more literature for 5.3.3.B2

Cloned(Commentary)

Cloned (Comment)	Organism
overexpression in Escherichia coli as a GST-fusion protein	Cutibacterium acnes

Crystallization (Commentary)

Crystallization (Comment)	Organism
six crystal structures in apo and product-bound forms, by single isomorphous replacement with anomalous scattering, SIRAS	Cutibacterium acnes

Organism

Organism	UniProt	Comment	Textmining
Cutibacterium acnes	Q6A8X5	-	-

Purification (Commentary)

Purification (Comment)	Organism
of the recombinant protein by glutathione sepharose chromatography	Cutibacterium acnes

Reaction

Reaction	Comment	Organism	Reaction ID
(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate	double bond isomerization	Cutibacterium acnes	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(6Z,9Z,12Z)-octadecatrienoic acid	linolenic acid	Cutibacterium acnes	(6Z,10E,12Z)-octadecatrienoic acid	-	?
(9Z,12Z)-octadecadienoic acid	linoleic acid	Cutibacterium acnes	(10E,12Z)-octadecadienoic acid	conjugated linoleic acid, double bound isomerization	?

Synonyms

Synonyms	Comment	Organism
PAI	polyenoic fatty acid isomerase from Propionibacterium acnes	Cutibacterium acnes
polyenoic fatty acid isomerase	-	Cutibacterium acnes

Cofactor

Cofactor	Comment	Organism	Structure
FAD	-	Cutibacterium acnes

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Release 2023.1 (January 2023)