Literature summary for 5.4.99.5 extracted from

Bartlett, P.A.; Nakagawa, Y.; Johnson, C.R.; Reich, S.H.; Luis, A.
Chorismate mutase inhibitors: synthesis and evaluation of some potential transition-state analogues (1988), J. Org. Chem., 53, 3195-3210.

No PubMed abstract available

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Inhibitors

Inhibitors	Comment	Organism	Structure
(2E)-8-exo-3-Hydroximino-8-hydroxy-2-oxabicyclo-[3.3.1]non-6-ene-5-carboxylic acid	poor	Escherichia coli
3-endo,6-exo-6-Hydroxy-7-bicyclo[3.3.1]-nonene-1,3-dicarboxylic acid	poor	Escherichia coli
3-endo,8-exo-8-Hydroxy-2-oxabicyclo[3.3.1]non-6-ene-3,5-dicarboxylic acid	potent	Escherichia coli
8-exo-8-Hydroxy-2-oxabicyclo[3.3.1]nona-3,6-diene-3,5-dicarboxylic acid	slight	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Chorismate	-	Escherichia coli	Prephenate	-	?

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Release 2023.1 (January 2023)