Application | Comment | Organism |
---|---|---|
drug development | the enzyme serves as a potential target for the development of inhibitors specific to the pathogen | Mycobacterium tuberculosis |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli BL21 (DE3) | Mycobacterium tuberculosis |
Crystallization (Comment) | Organism |
---|---|
analysis reveals the presence of two monomers in the asymmetric unit | Mycobacterium tuberculosis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-tryptophan | allosteric inhibitor | Mycobacterium tuberculosis |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
22000 | - |
monomer, SDS-PAGE | Mycobacterium tuberculosis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Chorismate | Mycobacterium tuberculosis | - |
Prephenate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
to homogeneity | Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Chorismate | - |
Mycobacterium tuberculosis | Prephenate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Mycobacterium tuberculosis |
Synonyms | Comment | Organism |
---|---|---|
chorismate mutase | - |
Mycobacterium tuberculosis |