Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | chorismate mutase activity is only detected when the Mg2+ is not present in the wild-type active site | Pseudomonas aeruginosa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Chorismate | Pseudomonas aeruginosa | - |
Prephenate | - |
? | |
additional information | Pseudomonas aeruginosa | isochorismate-pyruvate lyase, PchB EC 4.2.99.21, can also perform the chorismate mutase reaction | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
Chorismate = prephenate | via near attack conformation and transition state intermediates, reaction mechanism, overview | Pseudomonas aeruginosa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Chorismate | - |
Pseudomonas aeruginosa | Prephenate | - |
? | |
additional information | isochorismate-pyruvate lyase, PchB EC 4.2.99.21, can also perform the chorismate mutase reaction | Pseudomonas aeruginosa | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | enzyme structure comparisons of isochorismate-pyruvate lyase, PchB, with chorismate mutases, overview | Pseudomonas aeruginosa |
General Information | Comment | Organism |
---|---|---|
additional information | structure-function relationships of chorismate-utilizing enzymes, structure comparisons, overview | Pseudomonas aeruginosa |
physiological function | isochorismate-pyruvate lyase, PchB EC 4.2.99.21, can also perform a nonphysiological role as a chorismate mutase albeit with considerably lower catalytic efficiency | Pseudomonas aeruginosa |