Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme induction by 4-chlorobenzenesulfonic acid | Pseudomonas aeruginosa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cis,cis-muconate | Pseudomonas aeruginosa | i.e. cis,cis-hexadienedioate or (2Z,4Z)-hexa-2,4-dienedioate, in vitro activity | muconolactone | i.e. (2,5-dihydro-5-oxofuran-2-yl)acetate | ? | |
cis,cis-muconate | Pseudomonas aeruginosa RW41 | i.e. cis,cis-hexadienedioate or (2Z,4Z)-hexa-2,4-dienedioate, in vitro activity | muconolactone | i.e. (2,5-dihydro-5-oxofuran-2-yl)acetate | ? | |
additional information | Pseudomonas aeruginosa | the enzyme is involved in degradation of 4-chlorobenzenesulfonic acid, 4CBSA, the major polar by-product of the chemical synthesis of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl) ethane, DDT, overview, 4-chlorobenzenesulfonic acid catabolic pathway, overview | ? | - |
? | |
additional information | Pseudomonas aeruginosa RW41 | the enzyme is involved in degradation of 4-chlorobenzenesulfonic acid, 4CBSA, the major polar by-product of the chemical synthesis of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl) ethane, DDT, overview, 4-chlorobenzenesulfonic acid catabolic pathway, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | - |
- |
- |
Pseudomonas aeruginosa RW41 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native enzyme partially by anion exchange chromatography | Pseudomonas aeruginosa |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.017 | - |
substrate 3-chloro-cis,cis-muconate, crude enzyme extrat | Pseudomonas aeruginosa |
0.035 | - |
substrate cis,cis-muconate, crude enzyme extract | Pseudomonas aeruginosa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-chloro-cis,cis-muconate | - |
Pseudomonas aeruginosa | 4-chloro-muconolactone | unstable | ? | |
3-chloro-cis,cis-muconate | - |
Pseudomonas aeruginosa RW41 | 4-chloro-muconolactone | unstable | ? | |
3-chloro-cis,cis-muconate | in vitro activity | Pseudomonas aeruginosa | cis-dienelactone + protoanemonin + Cl- + H2O + CO2 | product ratio is 76:24, protoanemonin is antibiotically active | ? | |
3-chloro-cis,cis-muconate | in vitro activity | Pseudomonas aeruginosa RW41 | cis-dienelactone + protoanemonin + Cl- + H2O + CO2 | product ratio is 76:24, protoanemonin is antibiotically active | ? | |
cis,cis-muconate | - |
Pseudomonas aeruginosa | muconolactone | - |
? | |
cis,cis-muconate | i.e. cis,cis-hexadienedioate or (2Z,4Z)-hexa-2,4-dienedioate, in vitro activity | Pseudomonas aeruginosa | muconolactone | i.e. (2,5-dihydro-5-oxofuran-2-yl)acetate | ? | |
cis,cis-muconate | - |
Pseudomonas aeruginosa RW41 | muconolactone | - |
? | |
cis,cis-muconate | i.e. cis,cis-hexadienedioate or (2Z,4Z)-hexa-2,4-dienedioate, in vitro activity | Pseudomonas aeruginosa RW41 | muconolactone | i.e. (2,5-dihydro-5-oxofuran-2-yl)acetate | ? | |
additional information | the enzyme is involved in degradation of 4-chlorobenzenesulfonic acid, 4CBSA, the major polar by-product of the chemical synthesis of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl) ethane, DDT, overview, 4-chlorobenzenesulfonic acid catabolic pathway, overview | Pseudomonas aeruginosa | ? | - |
? | |
additional information | the enzyme is involved in degradation of 4-chlorobenzenesulfonic acid, 4CBSA, the major polar by-product of the chemical synthesis of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl) ethane, DDT, overview, 4-chlorobenzenesulfonic acid catabolic pathway, overview | Pseudomonas aeruginosa RW41 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
(chloro)-muconate cycloisomerase | - |
Pseudomonas aeruginosa |
MCI | - |
Pseudomonas aeruginosa |