Inhibitors | Comment | Organism | Structure |
---|---|---|---|
isodiospyrin | inhibits by direct binding to htopo I, inhibits relexation activity and kinase activity, antagonizes camptothecin-induced DNA cleavage by htopo I | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
SF2/ASF protein + ATP | kinase activity | Homo sapiens | ? | - |
? | |
supercoiled plasmid DNA pGEM-5T | relaxation | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
htopo I | - |
Homo sapiens |