Literature summary for 5.6.2.1 extracted from

Yang, F.; Nakajima, Y.; Kumagai, M.; Ohmiya, Y.; Ikeda, M.
The molecular mechanism regulating the autonomous circadian expression of Topoisomerase I in NIH3T3 cells (2009), Biochem. Biophys. Res. Commun., 380, 22-27.

Search for more literature for 5.6.2.1

Application

Application	Comment	Organism
medicine	TopoI is very important for the antitumor efficacy of many drugs, through the regulating the circadian clock genes and cell cycle control genes	Mus musculus

Protein Variants

Protein Variants	Comment	Organism
additional information	preparation of several mutant mTopoI promoters, including wild type and E1, E2, Dbox, E1/Dbox, E1/E2, and E1/E2/Dbox mutant types, and measurement of bioluminescence using a real-time monitoring assay	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q04750	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
NIH-3T3 cell	mouse embryonic fibroblast cell line	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
mTopoI	-	Mus musculus
topoI	-	Mus musculus
Topoisomerase I	-	Mus musculus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)