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Literature summary for 5.6.2.1 extracted from
- Targeting topoisomerase I: molecular mechanisms and cellular determinants of response to topoisomerase I inhibitors (2008), Expert Opin. Ther. Targets, 12, 1243-1256.
Application
| Application | Comment | Organism |
|---|---|---|
| drug development | inhibitors are antitumor agents | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ARC-111 | - |
Homo sapiens |  |
| camptothecin | - |
Homo sapiens | |
| diflomotecan | - |
Homo sapiens | |
| edotecarin | - |
Homo sapiens | |
| gimatecan | - |
Homo sapiens | |
| homocamptothecin | - |
Homo sapiens | |
| irinotecan | - |
Homo sapiens | |
| IT-101 | - |
Homo sapiens | |
| NSC-724998 | - |
Homo sapiens | |
| NSC-725776 | - |
Homo sapiens | |
| ST1968 | - |
Homo sapiens | |
| thiocamptothecin | - |
Homo sapiens | |
| topopyrone | - |
Homo sapiens | |
| topotecan | - |
Homo sapiens | |
| XMT-1001 | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| top I | - |
Homo sapiens |
| Topoisomerase I | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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