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Literature summary for 5.6.2.1 extracted from

  • Li, X.; Guo, L.; Deng, L.; Feng, D.; Ren, Y.; Chu, Y.; She, Q.; Huang, L.
    Deletion of the topoisomerase III gene in the hyperthermophilic archaeon Sulfolobus islandicus results in slow growth and defects in cell cycle control (2011), J. Genet. Genomics, 38, 253-259.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Sulfolobus islandicus F0NEW3 E233, spontaneous uracil-auxotrophic mutant derived from Sulfolobus islandicus Rey15A
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Sulfolobus islandicus Rey15A F0NEW3 E233, spontaneous uracil-auxotrophic mutant derived from Sulfolobus islandicus Rey15A
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Synonyms

Synonyms Comment Organism
SiRe_1176 locus name Sulfolobus islandicus
topoisomerase III
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Sulfolobus islandicus

General Information

General Information Comment Organism
malfunction topA deletion mutant strain DELTAtopA grows more slowly than the wild-type strain. The doubling time of the mutant is 11.9 h, as compared to 7.4 h for the wild-type strain, when both strains are grown in the rich medium at 75°C. The enzyme may not serve a critical role in the adaptation of thermophilic archaea to growth at high temperature Sulfolobus islandicus