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BRENDA support

Literature summary for 5.6.2.1 extracted from

  • Manzo, S.G.; Hartono, S.R.; Sanz, L.A.; Marinello, J.; De Biasi, S.; Cossarizza, A.; Capranico, G.; Chedin, F.
    DNA topoisomerase I differentially modulates R-loops across the human genome (2018), Genome Biol., 19, 100 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
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Homo sapiens
-

Synonyms

Synonyms Comment Organism
DNA topoisomerase I
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Homo sapiens
Top1
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Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme modulates the replication process via R-loop formation Homo sapiens