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Literature summary for 6.1.1.15 extracted from

  • Yaremchuk, A.; Kriklivyi, I.; Cusack, S.; Tukalo, M.
    Improved crystals of Thermus thermophilus prolyl-tRNA synthetase complexed with cognate tRNA obtained by crystallization from precipitate (2000), Acta Crystallogr. Sect. D, 56, 197-199.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
enzyme complexed with 2 different tRNAPro isoacceptors, 2 weeks, 32% saturated ammonium sulfate, X-ray diffraction structure determination at 2.8-3.1 A resolution, superior quality crystal are obtained within 5-6 months by slowly precipitation and growth, crystal packing analysis Thermus thermophilus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-proline + tRNAPro Thermus thermophilus
-
AMP + diphosphate + L-prolyl-tRNAPro
-
?

Organism

Organism UniProt Comment Textmining
Thermus thermophilus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-proline + tRNAPro
-
Thermus thermophilus AMP + diphosphate + L-prolyl-tRNAPro
-
?

Synonyms

Synonyms Comment Organism
Global RNA synthesis factor
-
Thermus thermophilus
Pro-tRNA synthetase
-
Thermus thermophilus
Proline translase
-
Thermus thermophilus
Proline--tRNA ligase
-
Thermus thermophilus
Prolyl RNA synthetase
-
Thermus thermophilus
Prolyl-transfer ribonucleate synthetase
-
Thermus thermophilus
Prolyl-transfer ribonucleic acid synthetase
-
Thermus thermophilus
Prolyl-transfer RNA synthetase
-
Thermus thermophilus
Prolyl-tRNA synthetase
-
Thermus thermophilus
ProRS
-
Thermus thermophilus
ProRSTT
-
Thermus thermophilus

Cofactor

Cofactor Comment Organism Structure
ATP
-
Thermus thermophilus