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Literature summary for 6.1.1.19 extracted from

  • Fu, Y.; Kim, Y.; Jin, K.S.; Kim, H.S.; Kim, J.H.; Wang, D.; Park, M.; Jo, C.H.; Kwon, N.H.; Kim, D.; Kim, M.H.; Jeon, Y.H.; Hwang, K.Y.; Kim, S.; Cho, Y.
    Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation (2014), Proc. Natl. Acad. Sci. USA, 111, 15084-15089 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.1.1.19

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Rosetta(DE3) cells Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
multisynthetase complex subcomplex comprising arginyl-tRNA synthetase, glutaminyl-tRNA synthetase, and the auxiliary factor aminoacyl tRNA synthetase complex-interacting multifunctional protein 1, hanging drop vapor diffusion method, using 5-10% (w/v) methylpentenediol, 0.1 M Tris HCl (pH 7.4), 0.2 M NaCl Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-arginine + tRNAArg Homo sapiens
-
 AMP + diphosphate + L-arginyl-tRNAArg
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P54136
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni2+ column chromatography, Mono-Q column chromatography, and Superdex 200 gel filtration Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-arginine + tRNAArg
-
 Homo sapiens AMP + diphosphate + L-arginyl-tRNAArg
-
 ?

Subunits

Subunits Comment Organism
? x * 66200, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
Arginyl-tRNA synthetase
-
 Homo sapiens
ArgRS
-
 Homo sapiens
RRS
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens