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Literature summary for 6.1.1.4 extracted from

  • Wright, H.T.; Nurse, K.C.; Goldstein, D.J.
    Naldixic acid, oxolinic acid, and novobiocin inhibit yeast glycyl- and leucyl-transfer RNA synthetases (1981), Science, 213, 455-456.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Nalidixic acid
-
Saccharomyces cerevisiae
novobiocin
-
Saccharomyces cerevisiae
Oxolinic acid
-
Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0003
-
tRNALeu
-
Saccharomyces cerevisiae
0.3
-
ATP
-
Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-leucine + tRNALeu
-
Saccharomyces cerevisiae AMP + diphosphate + L-leucyl-tRNALeu
-
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