Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.1.1.4 extracted from

  • Shin, S.H.; Kim, H.S.; Jung, S.H.; Xu, H.D.; Jeong, Y.B.; Chung, Y.J.
    Implication of leucyl-tRNA synthetase 1 (LARS1) over-expression in growth and migration of lung cancer cells detected by siRNA targeted knock-down analysis (2008), Exp. Mol. Med., 40, 229-236.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.1.1.4

Application

Application Comment Organism
medicine LARS1 plays roles in migration and growth of lung cancer cells, which suggest its potential implication in lung tumorigenesis Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information to explore the oncogenic potential of LARS1 over-expression in lung cancer, LARS1 is knocked-down using siRNA. LARS1 knock-down cells show reduced ability to migrate through transwell membrane and to form colonies in both soft agar and culture plate Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell LARS1 is over-expressed in lung cancer cell line A549 Homo sapiens
-
lung cancer cell LARS1 is over-expressed in lung cancer cells compared to control tissue Homo sapiens
-
lung epithelium cell line
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
LARS1
-
 Homo sapiens
leucyl-tRNA synthetase 1
-
 Homo sapiens