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Literature summary for 6.1.1.7 extracted from

  • Chihade, J.W.; Brown, J.R.; Schimmel, P.R.; De Pouplana, L.R.
    Origin of mitochondria in relation to evolutionary history of eukaryotic alanyl-tRNA synthetase (2000), Proc. Natl. Acad. Sci. USA, 97, 12153-12157.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.1.1.7

Cloned(Commentary)

Cloned (Comment) Organism
gene alaS, DNA sequence determination and analysis, phylogenetic origin Giardia intestinalis
gene alaS, DNA sequence determination and analysis, phylogenetic origin Dictyostelium discoideum
gene alaS, DNA sequence determination and analysis, phylogenetic origin Drosophila melanogaster

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Drosophila melanogaster 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-alanine + tRNAAla Giardia intestinalis
-
 AMP + diphosphate + L-alanyl-tRNAAla
-
 ?
ATP + L-alanine + tRNAAla Dictyostelium discoideum
-
 AMP + diphosphate + L-alanyl-tRNAAla
-
 ?
ATP + L-alanine + tRNAAla Drosophila melanogaster
-
 AMP + diphosphate + L-alanyl-tRNAAla
-
 ?

Organism

Organism UniProt Comment Textmining
Dictyostelium discoideum Q54Y20 gene alaS
-
Drosophila melanogaster Q9VRJ1 gene alaS is nuclear-encoded, mitochondrial isozyme
-
Giardia intestinalis Q9U022
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-alanine + tRNAAla
-
 Giardia intestinalis AMP + diphosphate + L-alanyl-tRNAAla
-
 ?
ATP + L-alanine + tRNAAla
-
 Dictyostelium discoideum AMP + diphosphate + L-alanyl-tRNAAla
-
 ?
ATP + L-alanine + tRNAAla
-
 Drosophila melanogaster AMP + diphosphate + L-alanyl-tRNAAla
-
 ?

Synonyms

Synonyms Comment Organism
Ala-tRNA synthetase
-
 Giardia intestinalis
Ala-tRNA synthetase
-
 Dictyostelium discoideum
Ala-tRNA synthetase
-
 Drosophila melanogaster
Alanine transfer RNA synthetase
-
 Giardia intestinalis
Alanine transfer RNA synthetase
-
 Dictyostelium discoideum
Alanine transfer RNA synthetase
-
 Drosophila melanogaster
Alanine translase
-
 Giardia intestinalis
Alanine translase
-
 Dictyostelium discoideum
Alanine translase
-
 Drosophila melanogaster
Alanine tRNA synthetase
-
 Giardia intestinalis
Alanine tRNA synthetase
-
 Dictyostelium discoideum
Alanine tRNA synthetase
-
 Drosophila melanogaster
Alanine-transfer RNA ligase
-
 Giardia intestinalis
Alanine-transfer RNA ligase
-
 Dictyostelium discoideum
Alanine-transfer RNA ligase
-
 Drosophila melanogaster
alanine-tRNA ligase
-
 Giardia intestinalis
alanine-tRNA ligase
-
 Dictyostelium discoideum
alanine-tRNA ligase
-
 Drosophila melanogaster
Alanyl-transfer ribonucleate synthetase
-
 Giardia intestinalis
Alanyl-transfer ribonucleate synthetase
-
 Dictyostelium discoideum
Alanyl-transfer ribonucleate synthetase
-
 Drosophila melanogaster
Alanyl-transfer ribonucleic acid synthetase
-
 Giardia intestinalis
Alanyl-transfer ribonucleic acid synthetase
-
 Dictyostelium discoideum
Alanyl-transfer ribonucleic acid synthetase
-
 Drosophila melanogaster
Alanyl-transfer RNA synthetase
-
 Giardia intestinalis
Alanyl-transfer RNA synthetase
-
 Dictyostelium discoideum
Alanyl-transfer RNA synthetase
-
 Drosophila melanogaster
Alanyl-tRNA synthetase
-
 Giardia intestinalis
Alanyl-tRNA synthetase
-
 Dictyostelium discoideum
Alanyl-tRNA synthetase
-
 Drosophila melanogaster
AlaRS
-
 Giardia intestinalis
AlaRS
-
 Dictyostelium discoideum
AlaRS
-
 Drosophila melanogaster
Synthase, alanyl-transfer ribonucleate
-
 Giardia intestinalis
Synthase, alanyl-transfer ribonucleate
-
 Dictyostelium discoideum
Synthase, alanyl-transfer ribonucleate
-
 Drosophila melanogaster

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Giardia intestinalis
ATP
-
 Dictyostelium discoideum
ATP
-
 Drosophila melanogaster