Inhibitors | Comment | Organism | Structure |
---|---|---|---|
8,11,14-Eicosatrienoate | - |
Homo sapiens | |
arachidonate | unlabeled arachidonate inhibits arachidonate activation | Homo sapiens | |
eicosapentaenoate | slight | Homo sapiens | |
oleate | not | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.03 | - |
arachidonate | - |
Homo sapiens | |
0.13 | - |
CoA | - |
Homo sapiens | |
0.5 | - |
ATP | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Homo sapiens | |
Mg2+ | Km: 2.5 mM | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + arachidonate + CoA | Homo sapiens | enzyme may control the level of free arachidonate in platelets, limiting prostaglandin synthesis by the unstimulated cell and capturing free arachidonate from extracellular sources | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 8,11,14-eicosatrienoate + CoA | - |
Homo sapiens | AMP + diphosphate + 8,11,14-eicosatrienoyl-CoA | - |
? | |
ATP + arachidonate + CoA | - |
Homo sapiens | AMP + diphosphate + arachidonoyl-CoA | - |
? | |
ATP + arachidonate + CoA | enzyme may control the level of free arachidonate in platelets, limiting prostaglandin synthesis by the unstimulated cell and capturing free arachidonate from extracellular sources | Homo sapiens | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Homo sapiens |