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Literature summary for 6.2.1.3 extracted from

  • Fujimoto, Y.; Onoduka, J.; Homma, K.J.; Yamaguchi, S.; Mori, M.; Higashi, Y.; Makita, M.; Kinoshita, T.; Noda, J.; Itabe, H.; Takanoa, T.
    Long-chain fatty acids induce lipid droplet formation in a cultured human hepatocyte in a manner dependent of acyl-CoA synthetase (2006), Biol. Pharm. Bull., 29, 2174-2180.
    View publication on PubMed
Search for more literature for 6.2.1.3

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by 4,4,10 beta-trimethyl-trans-decal-3 beta-ol Homo sapiens
Triacsin C significant inhibition Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
-
 Homo sapiens
-
Huh-7 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + laurate + CoA
-
 Homo sapiens AMP + diphosphate + lauroyl-CoA
-
 ?
ATP + linoleate + CoA
-
 Homo sapiens AMP + diphosphate + linoleoyl-CoA
-
 ?
ATP + myristate + CoA
-
 Homo sapiens AMP + diphosphate + myristoyl-CoA
-
 ?
ATP + oleate + CoA
-
 Homo sapiens AMP + diphosphate + oleoyl-CoA
-
 ?
ATP + palmitate + CoA
-
 Homo sapiens AMP + diphosphate + palmitoyl-CoA
-
 ?
ATP + stearate + CoA
-
 Homo sapiens AMP + diphosphate + stearoyl-CoA
-
 ?
additional information octanoate and decanoate are ineffective substrates Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
long chain acyl-CoA synthetase
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens