Protein Variants | Comment | Organism |
---|---|---|
A209E | the mutation is associated with encephalomyopathic mitochondrial DNA depletion syndrome | Homo sapiens |
E263K | the mutation is associated with encephalomyopathic mitochondrial DNA depletion syndrome | Homo sapiens |
H71R | the mutation is associated with encephalomyopathic mitochondrial DNA depletion syndrome | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + succinate + CoA | Homo sapiens | - |
GDP + phosphate + succinyl-CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P53597 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + succinate + CoA | - |
Homo sapiens | GDP + phosphate + succinyl-CoA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
succinate-CoA ligase | - |
Homo sapiens |
SUCLG1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
GTP | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme mutations cause the encephalomyopathic mitochondrial DNA depletion syndrome with methylmalonic aciduria | Homo sapiens |