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Literature summary for 6.2.1.61 extracted from
- Assembly of the Pseudomonas aeruginosa nonribosomal peptide siderophore pyochelin In vitro reconstitution of aryl-4,2-bisthiazoline synthetase activity from PchD, PchE, and PchF (1999), Biochemistry, 38, 14941-14954 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Pseudomonas aeruginosa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas aeruginosa | Q9RFM9 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant protein | Pseudomonas aeruginosa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (salicyl)adenylate + holo-[non-ribosomal peptide synthase PchE] | - |
Pseudomonas aeruginosa | AMP + salicyl-[non-ribosomal peptide synthase PchE] | - |
? |  |
| ATP + salicylate | - |
Pseudomonas aeruginosa | diphosphate + (salicyl)adenylate | - |
? | |
| ATP + salicylate + holo-[non-ribosomal peptide synthase PchE] | - |
Pseudomonas aeruginosa | AMP + diphosphate + salicyl-[non-ribosomal peptide synthase PchE] | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| (2,3-dihydroxybenzoyl)adenylate synthase | - |
Pseudomonas aeruginosa |
| pchD | - |
Pseudomonas aeruginosa |
| salicyl-AMP ligase | - |
Pseudomonas aeruginosa |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | enzyme is involved in biogenesis of the nonribosomal peptide siderophore pyochelin | Pseudomonas aeruginosa |
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Release 2023.1 (January 2023)
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