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Literature summary for 6.2.2.1 extracted from

  • Nayak, D.; Mahanta, N.; Mitchell, D.; Metcalf, W.
    Post-translational thioamidation of methyl-coenzyme M reductase, a key enzyme in methanogenic and methanotrophic Archaea (2017), eLife, 6, e29218 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + sulfide + a [methyl-coenzyme M reductase alpha-subunit McrA]-glycine465 Methanosarcina acetivorans
-
ADP + phosphate + a [methyl-coenzyme M reductase alpha-subunit McrA]-thioglycine465
-
?

Organism

Organism UniProt Comment Textmining
Methanosarcina acetivorans
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + sulfide + a [methyl-coenzyme M reductase alpha-subunit McrA]-glycine465
-
Methanosarcina acetivorans ADP + phosphate + a [methyl-coenzyme M reductase alpha-subunit McrA]-thioglycine465
-
?

Synonyms

Synonyms Comment Organism
ycaO
-
Methanosarcina acetivorans

General Information

General Information Comment Organism
malfunction enzyme loss is associated with growth defects Methanosarcina acetivorans