Literature summary for 6.3.1.2 extracted from

Goerg, B.; Qvartskhava, N.; Voss, P.; Grune, T.; Haeussinger, D.; Schliess, F.
Reversible inhibition of mammalian glutamine synthetase by tyrosine nitration (2007), FEBS Lett., 581, 84-90.

Search for more literature for 6.3.1.2

Activating Compound

Activating Compound	Comment	Organism	Structure
epicatechin	0.03 mM completely prevents inactivation of glutamine synthetase by peroxynitrite	Rattus norvegicus
epicatechin	0.03 mM completely prevents inactivation of glutamine synthetase by peroxynitrite	Ovis aries

Inhibitors

Inhibitors	Comment	Organism	Structure
peroxynitrite	0.005 mM, activity is decreased by about 25%	Ovis aries
peroxynitrite	0.005 mM, inactivation of the enzyme	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Ovis aries	-	-	-
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Ovis aries	-
brain cortex	-	Rattus norvegicus	-
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-Glu + NH4+	-	Rattus norvegicus	ADP + phosphate + L-Gln	-	?
ATP + L-Glu + NH4+	-	Ovis aries	ADP + phosphate + L-Gln	-	?

Synonyms

Synonyms	Comment	Organism
Glutamine synthetase	-	Rattus norvegicus
Glutamine synthetase	-	Ovis aries

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Release 2023.1 (January 2023)