Cloned (Comment) | Organism |
---|---|
- |
Lactococcus lactis |
General Stability | Organism |
---|---|
the tetramer is very stable even at dilute enzyme concentrations | Lactococcus lactis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CTP | cooperative inhibition | Lactococcus lactis | |
dCTP | very weak inhibitor | Lactococcus lactis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required, the activation curve for free Mg2+ concentration is greatly dependent on whether the concentration of ATP and UTP are near saturating | Lactococcus lactis |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
60000 | - |
2 * 60000 | Lactococcus lactis |
234000 | - |
gel filtration | Lactococcus lactis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Lactococcus lactis | in Lactococcus lactis the pyrG gene product is the only enzyme responsible for the amination of UTP to CTP | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lactococcus lactis | - |
subsp. cremonis | - |
Storage Stability | Organism |
---|---|
-20°C, stable for several months | Lactococcus lactis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + dUTP + NH4+ | half-saturating concentration of 0.6 mM for dUTP, it is unlikely that this reaction plays a significant physiological role | Lactococcus lactis | ADP + phosphate + dCTP | - |
? | |
ATP + UTP + NH4+ | - |
Lactococcus lactis | ADP + phosphate + CTP | - |
? | |
additional information | in Lactococcus lactis the pyrG gene product is the only enzyme responsible for the amination of UTP to CTP | Lactococcus lactis | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | 2 * 60000 | Lactococcus lactis |