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Literature summary for 6.3.4.2 extracted from
- Role of GTP in CTP synthetase from Ehrlich ascites tumor cells (1982), Biochem. Biophys. Res. Commun., 108, 286-291.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| GTP | essential activator when glutamine is the nitrogen source | Mus musculus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| adenylyl-iminodiphosphate | competitive with ATP | Mus musculus | |
| UTP | competitive with ATP | Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Ehrlich ascites carcinoma cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + UTP + NH4+ | - |
Mus musculus | ADP + phosphate + CTP | - |
? | |
| GTP + UTP + NH4+ | - |
Mus musculus | GDP + phosphate + CTP | - |
? | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.1 | - |
adenylyliminodiphosphate | pH 8.6 | Mus musculus | |
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