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Literature summary for 6.3.4.2 extracted from

  • Scheit, K.H.; Linke, H.J.
    Substrate specificity of CTP synthetase from E. coli (1981), Nucleic Acids Res., 9, 229-233.
    View publication on PubMed
Search for more literature for 6.3.4.2

Inhibitors

Inhibitors Comment Organism Structure
2-thiouridine 5'-triphosphate
-
 Escherichia coli
4-thiouridine 5'-triphosphate
-
 Escherichia coli
5-bromoUTP
-
 Escherichia coli
s4UTP
-
 Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + UTP + NH4+
-
 Escherichia coli ADP + phosphate + CTP
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.1
-
 2-thiouridine 5'-triphosphate pH 7.2, inhibition of glutamine reaction Escherichia coli
0.18
-
 5-bromoUTP pH 7.2, inhibition of glutamine reaction Escherichia coli
0.25
-
 2-thiouridine 5'-triphosphate pH 7.2, inhibition of ammonia reaction Escherichia coli
0.33
-
 1-beta-D-ribofuranosyl-2-thiouracil 5'-triphosphate pH 7.2, inhibition of glutamine reaction Escherichia coli
0.51
-
 s4UTP pH 7.2, inhibition of ammonia reaction Escherichia coli
0.53
-
 5-bromoUTP pH 7.2, inhibition of ammonia reaction Escherichia coli