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Literature summary for 6.3.4.2 extracted from

  • MacDonnell, J.E.; Lunn, F.A.; Bearne, S.L.
    Inhibition of E. coli CTP synthase by the "positive" allosteric effector GTP (2004), Biochim. Biophys. Acta, 1699, 213-220.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
GTP activates enzyme-catalyzed glutamine hydrolysis Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
GTP inhibition of glutamine-dependent CTP formation above 0.15 mM, inhibition of glutamine-dependent CTP formation in a concentration-dependent manner Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + UTP + Gln
-
Escherichia coli ADP + phosphate + CTP + Glu
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