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Literature summary for 6.3.4.2 extracted from
- Ack kinase regulates CTP synthase filaments during Drosophila oogenesis (2014), EMBO Rep., 15, 1184-1191 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | X2JCY2 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| germ cell | ovarian germline cell | Drosophila melanogaster | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CTPS | - |
Drosophila melanogaster |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | in ovarian germline cells CTPS filaments are catalytically active and their assembly is regulated by the non-receptor tyrosine kinase DAck. Egg chambers from flies deficient in DAck catalytic activity exhibit disrupted CTPS filament architecture and morphological defects that correlate with reduced fertility. Ovaries from these flies exhibit reduced levels of total RNA | Drosophila melanogaster |
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