Literature summary for 6.3.4.3 extracted from

Hori, T.; Sasaki, D.; Haruta, S.; Shigematsu, T.; Ueno, Y.; Ishii, M.; Igarashi, Y.
Detection of active, potentially acetate-oxidizing syntrophs in an anaerobic digester by flux measurement and formyltetrahydrofolate synthetase (FTHFS) expression profiling (2011), Microbiology, 157, 1980-1989.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + formate + tetrahydrofolate	uncultured microorganism	-	ADP + phosphate + 10-formyltetrahydrofolate	-	?
ATP + formate + tetrahydrofolate	Thermacetogenium phaeum	-	ADP + phosphate + 10-formyltetrahydrofolate	-	?
ATP + formate + tetrahydrofolate	Thermacetogenium phaeum DSM 12270	-	ADP + phosphate + 10-formyltetrahydrofolate	-	?

Organism

Organism	UniProt	Comment	Textmining
Thermacetogenium phaeum	D4QDA0	-	-
Thermacetogenium phaeum DSM 12270	D4QDA0	-	-
uncultured microorganism	A7BK03	-	-
uncultured microorganism	A7BK04	-	-
uncultured microorganism	A7BK05	-	-
uncultured microorganism	A7BK06	-	-
uncultured microorganism	A7BK07	-	-
uncultured microorganism	A7BK08	-	-
uncultured microorganism	A7BK09	-	-
uncultured microorganism	A7BK10	-	-
uncultured microorganism	A7BK11	-	-
uncultured microorganism	A7BK12	-	-
uncultured microorganism	A7BK13	-	-
uncultured microorganism	A7BK14	-	-
uncultured microorganism	A7BK15	-	-
uncultured microorganism	A7BK16	-	-
uncultured microorganism	A7BK17	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + formate + tetrahydrofolate	-	uncultured microorganism	ADP + phosphate + 10-formyltetrahydrofolate	-	?
ATP + formate + tetrahydrofolate	-	Thermacetogenium phaeum	ADP + phosphate + 10-formyltetrahydrofolate	-	?
ATP + formate + tetrahydrofolate	-	Thermacetogenium phaeum DSM 12270	ADP + phosphate + 10-formyltetrahydrofolate	-	?

Synonyms

Synonyms	Comment	Organism
Formyltetrahydrofolate synthetase	-	uncultured microorganism
Formyltetrahydrofolate synthetase	-	Thermacetogenium phaeum
FTHFS	-	uncultured microorganism
FTHFS	-	Thermacetogenium phaeum

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	uncultured microorganism
ATP	-	Thermacetogenium phaeum

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Release 2023.1 (January 2023)