Literature summary for 6.3.4.4 extracted from

Sun, H.; Li, N.; Wang, X.; Chen, T.; Shi, L.; Zhang, L.; Wang, J.; Wan, T.; Cao, X.
Molecular cloning and characterization of a novel muscle adenylosuccinate synthetase, AdSSL1, from human bone marrow stromal cells (2005), Mol. Cell. Biochem., 269, 85-94.

Search for more literature for 6.3.4.4

Cloned(Commentary)

Cloned (Comment)	Organism
overexpression in COS-7 cells	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	expression in COS-7 cells	Homo sapiens	5737	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
GTP + IMP + L-aspartate	Homo sapiens	first committed step in AMP synthesis. Isoenzyme AdSS1 has a potential role in muscle metabolism	GDP + phosphate + adenylosuccinate	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q8N142	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant enzyme	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
bone marrow	stromal cell, isoenzyme AdSS1	Homo sapiens	-
cardiac muscle	isoenzyme AdSS1	Homo sapiens	-
skeletal muscle	isoenzyme AdSS1	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GTP + IMP + L-aspartate	first committed step in AMP synthesis. Isoenzyme AdSS1 has a potential role in muscle metabolism	Homo sapiens	GDP + phosphate + adenylosuccinate	-	?

Synonyms

Synonyms	Comment	Organism
AdSSL1	-	Homo sapiens

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Release 2023.1 (January 2023)