Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli. The archaeal adenylosuccinate synthetase has a significant number of substitutions in residues that are conserved in all other homologous enzymes from bacteria to man. Despite theses differences the purA-like archaeal gene seems to be normally expressed and its product functions in vivo in bacteria, since it complements an Escherichia coli purA auxotroph | Pyrococcus sp. |
the archaeal adenylosuccinate synthase has a significant number of substitutions in residues that are conserved in all other homologous enzymes from bacteria to human. In Escherichia coli, the conserved residues are essential for catalytic activity and/or for the folded structure of the homodimer. Despite these drastic differences, the purA-like archaeal gene is normally expressed and its product functions in vivo in bacteria, since it complements an Escherichia coli purA auxotroph | Pyrococcus sp. |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pyrococcus sp. | Q59726 | - |
- |
Pyrococcus sp. ST700 | Q59726 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
purA | - |
Pyrococcus sp. |