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Literature summary for 6.3.4.7 extracted from

  • Holmes, E.W.; King, G.L.; Leyva, A.; Singer, S.C.
    A purine auxotroph deficient in phosphoribosylpyrophosphate amidotransferase and phosphoribosylpyrophosphate aminotransferase activities with normal activity of ribose-5-phosphate aminotransferase (1976), Proc. Natl. Acad. Sci. USA, 73, 2458-2461.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + ribose 5-phosphate + NH4+ Cricetulus griseus the enzyme does not play a significant role in the intracellular synthesis of 5-phosphoribosylamine in the Chinese hamster fibroblast cell line ?
-
?

Organism

Organism UniProt Comment Textmining
Cricetulus griseus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast wild-type and mutant cell line deficient in phosphoribosyldiphosphate amidotransferase and phosphoribosyldiphosphate aminotransferase activities with normal activity of ribose-5-phosphate aminotransferase activities Cricetulus griseus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + ribose 5-phosphate + carbamoylphosphate
-
Cricetulus griseus ADP + phosphate + 5-phosphoribosylamine + formate
-
?
ATP + ribose 5-phosphate + NH4+
-
Cricetulus griseus ADP + phosphate + 5-phosphoribosylamine
-
?
ATP + ribose 5-phosphate + NH4+ the enzyme does not play a significant role in the intracellular synthesis of 5-phosphoribosylamine in the Chinese hamster fibroblast cell line Cricetulus griseus ?
-
?