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Literature summary for 6.3.5.2 extracted from
- Guanosine-5'-phosphate synthetase and guanosine-5'-phosphate kinase in rat hepatomas and kidney tumors (1981), Biochim. Biophys. Acta, 658, 102-110.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0044 | - |
XMP | - |
Rattus norvegicus |  |
| 0.0112 | - |
GMP | - |
Rattus norvegicus | |
| 0.11 | - |
MgATP2- | - |
Rattus norvegicus | |
| 0.21 | - |
Gln | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 83000 | - |
gel filtration | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | enzyme activity is linked with cellular proliferation in differentiating, regenerating and neoplastic tissues | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| bone marrow | - |
Rattus norvegicus | - |
| brain | - |
Rattus norvegicus | - |
| heart | - |
Rattus norvegicus | - |
| hepatoma cell line | - |
Rattus norvegicus | - |
| intestine | mucosa | Rattus norvegicus | - |
| kidney | - |
Rattus norvegicus | - |
| kidney tumor cell | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
| lung | - |
Rattus norvegicus | - |
| skeletal muscle | - |
Rattus norvegicus | - |
| spleen | - |
Rattus norvegicus | - |
| testis | - |
Rattus norvegicus | - |
| thymus | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + XMP + Gln | - |
Rattus norvegicus | AMP + diphosphate + GMP + Glu | - |
? | |
| additional information | enzyme activity is linked with cellular proliferation in differentiating, regenerating and neoplastic tissues | Rattus norvegicus | ? | - |
? | |
| XMP + Mg-ATP2- | - |
Rattus norvegicus | adenyl-XMP + diphosphate + Mg2+ | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.6 | 7.8 | - |
Rattus norvegicus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7.6 | 7.8 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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