Activating Compound | Comment | Organism | Structure |
---|---|---|---|
acetyl-CoA | activates in presence of either L-Asp or 2-oxoglutarate but does not activate in absence of these dicarboxylic acids. Trinitrobenzenesulfonate causes selective loss of the capacity for activation by acetyl-CoA | Aspergillus nidulans |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-oxoglutarate | competitive with respect to pyruvate and at lower concentrations uncompetitive with respect to HCO3- | Aspergillus nidulans | |
L-Asp | competitive with respect to HCO3-, non-competitive with respect to pyruvate and MgATP2- | Aspergillus nidulans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus nidulans | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Aspergillus nidulans |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + pyruvate + HCO3- | - |
Aspergillus nidulans | ADP + phosphate + oxaloacetate | - |
? |