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Literature summary for 6.4.1.2 extracted from

  • Park, H.; Kaushik, V.K.; Constant, S.; Prentki, M.; Przybytkowski, E.; Ruderman, N.B.; Saha, A.K.
    Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise (2002), J. Biol. Chem., 277, 32571-32577.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + acetyl-CoA + HCO3- Rattus norvegicus key enzyme of fatty acid biosynthesis, involved in regulation of fatty acid uptake into mitochondria ADP + phosphate + malonyl-CoA
-
?
ATP + acetyl-CoA + HCO3- Rattus norvegicus Sprague-Dawley key enzyme of fatty acid biosynthesis, involved in regulation of fatty acid uptake into mitochondria ADP + phosphate + malonyl-CoA
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
male sprague-dawley rats
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein enzyme is phosphorylated and inactivated by AMP-activated protein kinase Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + acetyl-CoA + HCO3-
-
Rattus norvegicus ADP + phosphate + malonyl-CoA
-
?
ATP + acetyl-CoA + HCO3- key enzyme of fatty acid biosynthesis, involved in regulation of fatty acid uptake into mitochondria Rattus norvegicus ADP + phosphate + malonyl-CoA
-
?
ATP + acetyl-CoA + HCO3-
-
Rattus norvegicus Sprague-Dawley ADP + phosphate + malonyl-CoA
-
?
ATP + acetyl-CoA + HCO3- key enzyme of fatty acid biosynthesis, involved in regulation of fatty acid uptake into mitochondria Rattus norvegicus Sprague-Dawley ADP + phosphate + malonyl-CoA
-
?

Cofactor

Cofactor Comment Organism Structure
biotin enzyme-bound Rattus norvegicus