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Literature summary for 6.5.1.1 extracted from

  • Tomkinson, A.E.; Roberts, E.; Daly, G.; Totty, N.F.; Lindahl, T.
    Three distinct DNA ligases in mammalian cells (1991), J. Biol. Chem., 266, 21728-21735.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Bos taurus
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calf
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Bos taurus
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DNA ligase I, II, III
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Purification (Commentary)

Purification (Comment) Organism
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Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
thymus
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Bos taurus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m DNA ligase I joins single strand breaks in double stranded DNA, is active on oligo(dT) hybridized to poly(dA), and does not catalyze the joining of oligo(dT)*poly(rA). DNA ligase II and III catalyze the joining of oligo(dT)*poly(rA) Bos taurus AMP + diphosphate + (deoxyribonucleotide)n+m
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