Any feedback?
Literature summary for 6.5.1.1 extracted from
- Induction of DNA ligase I by 1-beta-D-arabinosylcytosine and aphidicolin in MiaPaCa human pancreatic cancer cells (2002), Exp. Cell Res., 280, 90-96.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | Homo sapiens | DNA ligase I might be involved in repair of DNA strand breaks prior to the resumption of DNA synthesis | AMP + diphosphate + (deoxyribonucleotide)m+n | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
3fold increase in DNA ligase I protein levels after exposure of MiaPa cells to 1-beta-arabinosylcytosine, DNA ligase I is also induced by aphidicolin | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| MiaPaCa cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | - |
Homo sapiens | AMP + diphosphate + (deoxyribonucleotide)m+n | - |
? | |
| ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | DNA ligase I might be involved in repair of DNA strand breaks prior to the resumption of DNA synthesis | Homo sapiens | AMP + diphosphate + (deoxyribonucleotide)m+n | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DNA ligase I | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
