Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.5.1.1 extracted from

  • Liang, L.; Deng, L.; Nguyen, S.C.; Zhao, X.; Maulion, C.D.; Shao, C.; Tischfield, J.A.
    Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks (2008), Nucleic Acids Res., 36, 3297-3310.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.5.1.1

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
 Homo sapiens 5634
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
46BR cell
-
 Homo sapiens
-
fibroblast
-
 Homo sapiens
-
HTD-114 cell
-
 Homo sapiens
-
WI-38 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
 Homo sapiens AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?

Synonyms

Synonyms Comment Organism
DNA ligase I DNA ligase I is required for 10bp-microhomology-mediated end joining Homo sapiens
DNA ligase III DNA ligase III is required in microhomology-mediated end joining Homo sapiens
DNA ligase IV DNA ligase IV is not required in microhomology-mediated end joining but facilitates Ku-dependent nonhomologous end-joining Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens