Cloned (Comment) | Organism |
---|---|
expressed as His6-tagged protein in Escherichia coli | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | Homo sapiens | - |
AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
nickel-agarose bead chromatography, ion exchange chromatography, and gel filtration | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | - |
Homo sapiens | AMP + diphosphate + (deoxyribonucleotide)n+m | - |
? | |
additional information | the DNA binding domain of human DNA ligase I interacts with both nicked DNA and the DNA sliding clamps, proliferating cell nuclear antigen and hRad9-hRad1-hHus1 | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DNA ligase I | - |
Homo sapiens |
LIG1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |