Literature summary for 7.1.1.1 extracted from

Jackson, J.B.; Lever, T.M.; Rydstr�m, J.; Persson, B.; Carlenor, E.
Proton-translocating transhydrogenase from photosynthetic bacteria (1991), Biochem. Soc. Trans., 19, 573-575.

Search for more literature for 7.1.1.1

Activating Compound

Activating Compound	Comment	Organism	Structure
carbonylcyanide-4-trifluoromethoxyphenyl hydrazone	0.002 mM stimulates the rate of the forward reaction by 8fold and of the reverse reaction by 10fold	Escherichia coli

Inhibitors

Inhibitors	Comment	Organism	Structure
valinomycin	-	Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
48000	-	1 * 50000 + 1 * 48000, SDS-PAGE	Escherichia coli
50000	-	1 * 50000 + 1 * 48000, SDS-PAGE	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
NADPH + NAD+ + H+[side 1]	Escherichia coli	-	NADP+ + NADH + H+[side 2]	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
DEAE-Sepharose column chromatography and hydroxyapatite column chromatography	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
NADPH + NAD+ + H+[side 1]	-	Escherichia coli	NADP+ + NADH + H+[side 2]	-	?
NADPH + oxidized acetylpyridine adenine dinucleotide + H+[side 1]	-	Escherichia coli	NADP+ + reduced acetylpyridine adenine dinucleotide + H+[side 2]	-	?
thio-NADPH + NAD+ + H+[side 1]	-	Escherichia coli	thio-NADP+ + NADH + H+[side 2]	-	?

Subunits

Subunits	Comment	Organism
heterodimer	1 * 50000 + 1 * 48000, SDS-PAGE	Escherichia coli

Synonyms

Synonyms	Comment	Organism
H+-thase	-	Escherichia coli
nicotinamide adenine dinucleotide H +-transhydrogenase	-	Escherichia coli
proton-translocating transhydrogenase	-	Escherichia coli

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Release 2023.1 (January 2023)