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Literature summary for 7.1.1.1 extracted from
- Proton translocation by transhydrogenase (2003), FEBS Lett., 545, 18-24.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Escherichia coli | 16020 | - |
| membrane | - |
Rhodospirillum rubrum | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADH + NADP+ | Escherichia coli | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, provides NADPH for biosynthesis and reduction of glutathione | NAD+ + NADPH | - |
r |  |
| NADH + NADP+ | Rhodospirillum rubrum | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, provides NADPH for biosynthesis and reduction of glutathione | NAD+ + NADPH | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
| Rhodospirillum rubrum | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADH + NADP+ | - |
Escherichia coli | NAD+ + NADPH | - |
r | |
| NADH + NADP+ | - |
Rhodospirillum rubrum | NAD+ + NADPH | - |
r | |
| NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, provides NADPH for biosynthesis and reduction of glutathione | Escherichia coli | NAD+ + NADPH | - |
r | |
| NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, provides NADPH for biosynthesis and reduction of glutathione | Rhodospirillum rubrum | NAD+ + NADPH | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | monomers composed of three domains, dI, dII, and dIII | Escherichia coli |
| dimer | monomers composed of three domains, dI, dII, and dIII | Rhodospirillum rubrum |
| trimer | dI2dIII trimers formed in mixtures of recombinant dI and dIII domains | Escherichia coli |
| trimer | dI2dIII trimers formed in mixtures of recombinant dI and dIII domains | Rhodospirillum rubrum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD(P)+ | - |
Escherichia coli | |
| NAD(P)+ | - |
Rhodospirillum rubrum | |
| NAD(P)H | - |
Escherichia coli | |
| NAD(P)H | - |
Rhodospirillum rubrum | |
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Release 2023.1 (January 2023)
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