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Literature summary for 7.1.1.2 extracted from
- Isolation and characterization of complex I, rotenone-sensitive NADH:ubiquinone oxidoreductase, from the procyclic forms of Trypanosoma brucei (2001), Eur. J. Biochem., 268, 3075-3082.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| capsaicin | - |
Trypanosoma brucei |  |
| piercidin A | - |
Trypanosoma brucei | |
| rotenone | - |
Trypanosoma brucei | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrial membrane | - |
Trypanosoma brucei | 31966 | - |
| mitochondrion | membrane | Trypanosoma brucei | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Trypanosoma brucei | - |
brucei | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Trypanosoma brucei |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | procyclic form of the organism | Trypanosoma brucei | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADH + ubiquinone | - |
Trypanosoma brucei | NAD+ + ubiquinol | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | four polypeptides, of 15000 Da, 20000 Da, 38000 Da and 51000 Da are identified as subunits of complex I by SDS-PAGE | Trypanosoma brucei |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Trypanosoma brucei | |
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