Activating Compound | Comment | Organism | Structure |
---|---|---|---|
riboflavin | 0.001 mg/ml | Caenorhabditis elegans |
Protein Variants | Comment | Organism |
---|---|---|
A352V | mutation in the 51 kDa subunit, shows mildly decreased NADH-dependent respiration and lactic acidosis | Caenorhabditis elegans |
A443F | mutation in the 51 kDa subunit, shows decreased NADH-dependent respiration and lactic acidosis | Caenorhabditis elegans |
T434M | mutation in the 51 kDa subunit, shows decreased NADH-dependent respiration and lactic acidosis | Caenorhabditis elegans |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
rotenone | 0.002 mg/ml | Caenorhabditis elegans |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Caenorhabditis elegans | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
51000 | - |
nuo-I subunit of wild type enzyme, SDS-PAGE | Caenorhabditis elegans |
950000 | - |
whole wild type enzyme, SDS-PAGE | Caenorhabditis elegans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADH + 2,3-dimethoxy-5-methyl-6-[(6-methyl-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)methyl]benzo-1,4-quinone | - |
Caenorhabditis elegans | NAD+ + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
complex I | - |
Caenorhabditis elegans |
NADH-ubiquinone oxidoreductase | - |
Caenorhabditis elegans |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Caenorhabditis elegans |