Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | in m.1627C animals, the enzyme activity value under normal oxygen is significantly lower than that under simulated hypoxia | Gallus gallus |
Application | Comment | Organism |
---|---|---|
additional information | missense mutation in the MT-ND5 subunit of NADH dehydrogenase in Tibet chicken breed. Significant differences between animals carrying mitochondria with the EF493865.1:m.1627A versus EF493865.1:m.1627C alleles for respiratory control ratio and enzyme activity. MT-ND5 gene variation is significantly associated with brain mitochondrial respiratory function in Tibet chicken embryos under hypoxia, which identifies MT-ND5 as a candidate gene for adaptation to hypoxia (or high hatchability under hypoxia) in Tibet chickens | Gallus gallus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | in m.1627A animals, the enzyme activity value under normal oxygen is significantly higher than that under simulated hypoxia | Gallus gallus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Gallus gallus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
Tibet chicken | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Gallus gallus | - |
embryo | - |
Gallus gallus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADH + ubiquinone + H+ | - |
Gallus gallus | NAD+ + ubiquinol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
complex I | - |
Gallus gallus |
NADH dehydrogenase | - |
Gallus gallus |