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Literature summary for 7.1.1.9 extracted from
- Nitric oxide and peroxynitrite cause irreversible increases in the K(m) for oxygen of mitochondrial cytochrome oxidase: in vitro and in vivo studies (2003), Biochim. Biophys. Acta, 1607, 27-34.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| CO | competitive and reversible | Bos taurus |  |
| nitric oxide | competitive and reversible. Nanomolar levels inhibit the enzyme by competing with oxygen at the enzymes heme-copper active site. This raises the Km for cellular respiration into the physiological range | Bos taurus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Bos taurus | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Bos taurus | - |
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Release 2023.1 (January 2023)
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