Application | Comment | Organism |
---|---|---|
medicine | lack of energy after traumatic brain injury caused by inhibition of CcO may be an important aspect of trauma pathology | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NO | increased NO production after traumatic brain injury triggers inhibition of CcO. Traumatic brain injury leads to CcO inhibition and dramatically decreased ATP levels in brain cortex. CcO inhibition can be partially restored by application of iNOS antisense oligonucleotides prior to traumatic brain injury, which leads to a normalization of ATP levels similar to the controls | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male sprague-dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain cortex | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
CCO | - |
Rattus norvegicus |
cytochrome c oxidase | - |
Rattus norvegicus |