Literature summary for 7.1.1.9 extracted from

Kaplan, P.; Tatarkova, Z.; Racay, P.; Lehotsky, J.; Pavlikova, M.; Dobrota, D.
Oxidative modifications of cardiac mitochondria and inhibition of cytochrome c oxidase activity by 4-hydroxynonenal (2007), Redox Rep., 12, 211-218.

Search for more literature for 7.1.1.9

Inhibitors

Inhibitors	Comment	Organism	Structure
4-hydroxynonenal	time- and concentration-dependent inhibition of cytochrome c oxidase activity. Superoxide dismutase and catalase and the HO radical scavenger mannitol partially prevent inhibition of cytochrome c oxidase activity	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Rattus norvegicus	5739	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
heart	-	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
cytochrome c oxidase	-	Rattus norvegicus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0083	-	-	Rattus norvegicus	4-hydroxynonenal

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Release 2023.1 (January 2023)