Inhibitors | Comment | Organism | Structure |
---|---|---|---|
nitric oxide | nitric oxide generated from NaNO2 decreases cellular oxygen consumption and inhibits CcOX activity | Rattus norvegicus | |
potassium cyanide | cyanide binds to the binuclear heme center of cytochrome c oxidase, complete inhibition at 0.02 mM, pretreatment with NaNO2 reverses potassium cyanide-mediated inhibition of CcOX activity | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
N-27 cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ferrocytochrome c + O2 + H+ | - |
Rattus norvegicus | ferricytochrome c + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CcOX | - |
Rattus norvegicus |
cytochrome c oxidase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | binuclear heme center | Rattus norvegicus |