Any feedback?
Literature summary for 7.1.1.9 extracted from
- Monomeric structure of an active form of bovine cytochrome c oxidase (2019), Proc. Natl. Acad. Sci. USA, 116, 19945-19951 .
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| oxidized and reduced structures of monomer with resolutions of 1.85 and 1.95 A, respectively. A hydrogen bond network of water molecules is formed at the entry surface of the proton transfer pathway, in monomeric CcO, whereas this network is altered in dimeric CcO. Phospholipid structures are found with the protein complex, two cardiolipins are found at the interface region of the supercomplex | Bos taurus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Bos taurus | 16020 | - |
| mitochondrion | - |
Bos taurus | 5739 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 210000 | - |
gel filtration | Bos taurus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | P00396 | subunit 1 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Bos taurus | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 210000, calculated from sequence | Bos taurus |
| More | dilution of the purified protein causes dissociation of the dimer to the monomer. When the pH is raised to 7.4 or 8.5, the protein also shifts from the dimer to the monomer. In solution, CcO is in an equilibrium state between the dimer and monomer | Bos taurus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CCO | - |
Bos taurus |
| MT-CO1 | - |
Bos taurus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
