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Literature summary for 7.1.2.2 extracted from

  • Jones, P.C.
    Introduction of a carboxyl group in the first transmembrane helix of Escherichia coli F1F0 ATPase subunit c and cytoplasmic pH regulation (2001), J. Bacteriol., 183, 1524-1530.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.1.2.2

Protein Variants

Protein Variants Comment Organism
D61G growth on succinate is abolished, reduced ATPase activity Escherichia coli
I28D growth on succinate is reduced to 25% of the wild-type value,reduced ATPase activity Escherichia coli
I28D/D61G growth on succinate is abolished, reduced ATPase activity Escherichia coli
I28E reduced ATPase activity Escherichia coli
I28E/D61G growth on succinate is abolished, reduced ATPase activity Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + H+/in Escherichia coli the primary function of the enzyme is H+ pumping for cytoplasmic pH regulation ADP + phosphate + H+/out
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + H+/in the primary function of the enzyme is H+ pumping for cytoplasmic pH regulation Escherichia coli ADP + phosphate + H+/out
-
 ?
ATP + H2O + H+/in the side chain at position 28 is part of the ion binding pocket Escherichia coli ADP + phosphate + H+/out
-
 ?