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Literature summary for 7.1.3.1 extracted from

  • Islam, K.M.; Miyoshi, T.; Isobe, T.; Kasuga-Aoki, H.; Arakawa, T.; Matsumoto, Y.; Yokomizo, Y.; Tsuji, N.
    Temperature and metal ions-dependent activity of the family I inorganic pyrophosphatase from the swine roundworm Ascaris suum (2004), J. Vet. Med. Sci., 66, 221-223.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Ascaris suum

Inhibitors

Inhibitors Comment Organism Structure
Ca2+
-
Ascaris suum

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ 35% of the activity with Mg2+ Ascaris suum
Cu2+ 35% of the activity with Mg2+ Ascaris suum
Mg2+ required, highest activity at 5 mM Ascaris suum
additional information other metal ions can partially replace Mg2+, activation decreases in the order Mg2+, Co2+, Cu2+, Fe2+, Zn2+, Mn2+ Ascaris suum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
diphosphate + H2O + H+[side 1] Ascaris suum important for energy metabolism, provides energy for biosynthetic reactions, diphosphate hydrolysis dependent proton translocation 2 phosphate + H+[side 2]
-
?

Organism

Organism UniProt Comment Textmining
Ascaris suum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diphosphate + H2O + H+[side 1]
-
Ascaris suum 2 phosphate + H+[side 2]
-
?
diphosphate + H2O + H+[side 1] important for energy metabolism, provides energy for biosynthetic reactions, diphosphate hydrolysis dependent proton translocation Ascaris suum 2 phosphate + H+[side 2]
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
55
-
-
Ascaris suum

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
20 65
-
Ascaris suum

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
40
-
stable in the absence of Mg2+ Ascaris suum
50
-
stable in the presence of Mg2+ Ascaris suum