BRENDA - Enzyme Database
show all sequences of 7.2.1.1

Sodium-translocating NADH:quinone oxidoreductase as a redox-driven ion pump

Verkhovsky, M.I.; Bogachev, A.V.; Biochim. Biophys. Acta 1797, 738-746 (2010)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Haemophilus influenzae
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Klebsiella pneumoniae
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Neisseria gonorrhoeae
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Neisseria meningitidis
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Porphyromonas gingivalis
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Pseudomonas aeruginosa
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Vibrio alginolyticus
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Vibrio harveyi
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Yersinia pestis
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Vibrio cholerae
Ag+
-
Azotobacter vinelandii
Ag+
-
Haemophilus influenzae
Ag+
-
Neisseria gonorrhoeae
Ag+
-
Neisseria meningitidis
Ag+
-
Porphyromonas gingivalis
Ag+
-
Pseudomonas aeruginosa
Ag+
-
Vibrio cholerae
Ag+
-
Vibrio harveyi
Ag+
-
Yersinia pestis
Ag+
-
Vibrio alginolyticus
Cd2+
-
Azotobacter vinelandii
Cd2+
-
Haemophilus influenzae
Cd2+
-
Klebsiella pneumoniae
Cd2+
-
Neisseria gonorrhoeae
Cd2+
-
Neisseria meningitidis
Cd2+
-
Porphyromonas gingivalis
Cd2+
-
Pseudomonas aeruginosa
Cd2+
-
Vibrio alginolyticus
Cd2+
-
Vibrio cholerae
Cd2+
-
Vibrio harveyi
Cd2+
-
Yersinia pestis
Cu2+
-
Azotobacter vinelandii
Cu2+
-
Haemophilus influenzae
Cu2+
-
Klebsiella pneumoniae
Cu2+
-
Neisseria gonorrhoeae
Cu2+
-
Neisseria meningitidis
Cu2+
-
Porphyromonas gingivalis
Cu2+
-
Pseudomonas aeruginosa
Cu2+
-
Vibrio alginolyticus
Cu2+
-
Vibrio cholerae
Cu2+
-
Vibrio harveyi
Cu2+
-
Yersinia pestis
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Azotobacter vinelandii
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Klebsiella pneumoniae
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Neisseria gonorrhoeae
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Neisseria meningitidis
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Porphyromonas gingivalis
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Pseudomonas aeruginosa
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Vibrio alginolyticus
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Vibrio cholerae
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Vibrio harveyi
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Yersinia pestis
additional information
Na+-NQR from Azotobacter vinelandii is not sensitive to low 2-n-heptyl-4-hydroxyquinoline-N-oxide concentrations
Azotobacter vinelandii
additional information
korormicin has no effect on the enzyme from Haemophilus influenza
Haemophilus influenzae
additional information
Na+-NQR from Klebsiella pneumoniae is fully resistant to either Ag+ or N-ethylmaleimide
Klebsiella pneumoniae
N-ethylmaleimide
-
Azotobacter vinelandii
N-ethylmaleimide
-
Haemophilus influenzae
N-ethylmaleimide
-
Neisseria gonorrhoeae
N-ethylmaleimide
-
Neisseria meningitidis
N-ethylmaleimide
-
Porphyromonas gingivalis
N-ethylmaleimide
-
Pseudomonas aeruginosa
N-ethylmaleimide
-
Vibrio alginolyticus
N-ethylmaleimide
-
Vibrio cholerae
N-ethylmaleimide
-
Vibrio harveyi
N-ethylmaleimide
-
Yersinia pestis
Pb2+
-
Azotobacter vinelandii
Pb2+
-
Haemophilus influenzae
Pb2+
-
Klebsiella pneumoniae
Pb2+
-
Neisseria gonorrhoeae
Pb2+
-
Neisseria meningitidis
Pb2+
-
Porphyromonas gingivalis
Pb2+
-
Pseudomonas aeruginosa
Pb2+
-
Vibrio alginolyticus
Pb2+
-
Vibrio cholerae
Pb2+
-
Yersinia pestis
Pb2+
-
Vibrio harveyi
Zn2+
-
Azotobacter vinelandii
Zn2+
-
Haemophilus influenzae
Zn2+
-
Klebsiella pneumoniae
Zn2+
-
Neisseria gonorrhoeae
Zn2+
-
Neisseria meningitidis
Zn2+
-
Porphyromonas gingivalis
Zn2+
-
Pseudomonas aeruginosa
Zn2+
-
Vibrio alginolyticus
Zn2+
-
Vibrio cholerae
Zn2+
-
Vibrio harveyi
Zn2+
-
Yersinia pestis
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Azotobacter vinelandii
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Haemophilus influenzae
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Klebsiella pneumoniae
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Neisseria gonorrhoeae
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Neisseria meningitidis
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Porphyromonas gingivalis
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Pseudomonas aeruginosa
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Vibrio alginolyticus
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Vibrio cholerae
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Vibrio harveyi
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Yersinia pestis
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
21500
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
22700
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
27500
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
45200
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
45400
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
48400
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Haemophilus influenzae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio harveyi
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Pseudomonas aeruginosa
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria gonorrhoeae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria meningitidis
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Klebsiella pneumoniae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Azotobacter vinelandii
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Yersinia pestis
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Porphyromonas gingivalis
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio cholerae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio alginolyticus
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
additional information
Haemophilus influenzae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Vibrio harveyi
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Pseudomonas aeruginosa
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Neisseria gonorrhoeae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Neisseria meningitidis
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Klebsiella pneumoniae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Azotobacter vinelandii
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Yersinia pestis
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Porphyromonas gingivalis
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Vibrio cholerae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Vibrio alginolyticus
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Haemophilus influenzae
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Vibrio harveyi
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Pseudomonas aeruginosa
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Neisseria gonorrhoeae
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Neisseria meningitidis
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Klebsiella pneumoniae
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Azotobacter vinelandii
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Yersinia pestis
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Porphyromonas gingivalis
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Vibrio cholerae
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Vibrio alginolyticus
Na+-NQR does not oxidize NADPH
?
-
-
-
NADH + H+ + ubiquinone + 2 Na+/in
Haemophilus influenzae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Vibrio harveyi
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Pseudomonas aeruginosa
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Neisseria gonorrhoeae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Neisseria meningitidis
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Klebsiella pneumoniae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Azotobacter vinelandii
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Yersinia pestis
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Porphyromonas gingivalis
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Vibrio cholerae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Vibrio alginolyticus
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Haemophilus influenzae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio harveyi
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Pseudomonas aeruginosa
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria gonorrhoeae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria meningitidis
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Klebsiella pneumoniae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Azotobacter vinelandii
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Yersinia pestis
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Porphyromonas gingivalis
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio cholerae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio alginolyticus
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Azotobacter vinelandii
-
-
-
Haemophilus influenzae
-
-
-
Klebsiella pneumoniae
-
-
-
Neisseria gonorrhoeae
-
-
-
Neisseria meningitidis
-
-
-
Porphyromonas gingivalis
-
-
-
Pseudomonas aeruginosa
-
-
-
Vibrio alginolyticus
-
-
-
Vibrio cholerae
-
-
-
Vibrio harveyi
-
-
-
Yersinia pestis
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Haemophilus influenzae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio harveyi
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Pseudomonas aeruginosa
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria gonorrhoeae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria meningitidis
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Klebsiella pneumoniae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Azotobacter vinelandii
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Yersinia pestis
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Porphyromonas gingivalis
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio cholerae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio alginolyticus
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Haemophilus influenzae
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Vibrio harveyi
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Pseudomonas aeruginosa
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Neisseria gonorrhoeae
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Neisseria meningitidis
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Klebsiella pneumoniae
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Azotobacter vinelandii
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Yersinia pestis
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Porphyromonas gingivalis
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Vibrio cholerae
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Vibrio alginolyticus
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Haemophilus influenzae
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Vibrio harveyi
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Pseudomonas aeruginosa
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Neisseria gonorrhoeae
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Neisseria meningitidis
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Klebsiella pneumoniae
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Azotobacter vinelandii
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Yersinia pestis
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Porphyromonas gingivalis
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Vibrio cholerae
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Vibrio alginolyticus
?
-
-
-
-
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Haemophilus influenzae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio harveyi
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Pseudomonas aeruginosa
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria gonorrhoeae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria meningitidis
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Klebsiella pneumoniae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Azotobacter vinelandii
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Yersinia pestis
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Porphyromonas gingivalis
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio cholerae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio alginolyticus
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Haemophilus influenzae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio harveyi
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Pseudomonas aeruginosa
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria gonorrhoeae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria meningitidis
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Klebsiella pneumoniae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Azotobacter vinelandii
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Yersinia pestis
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Porphyromonas gingivalis
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio cholerae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio alginolyticus
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
Subunits
Subunits
Commentary
Organism
heterohexamer
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
Cofactor
Cofactor
Commentary
Organism
Structure
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Azotobacter vinelandii
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Haemophilus influenzae
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Klebsiella pneumoniae
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Neisseria gonorrhoeae
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Neisseria meningitidis
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Porphyromonas gingivalis
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Pseudomonas aeruginosa
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Vibrio alginolyticus
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Vibrio cholerae
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Vibrio harveyi
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Yersinia pestis
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Azotobacter vinelandii
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Haemophilus influenzae
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Klebsiella pneumoniae
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Neisseria gonorrhoeae
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Neisseria meningitidis
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Porphyromonas gingivalis
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Pseudomonas aeruginosa
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Vibrio alginolyticus
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Vibrio cholerae
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Vibrio harveyi
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Yersinia pestis
NADH
Na+-NQR is specific to NADH
Azotobacter vinelandii
NADH
Na+-NQR is specific to NADH
Haemophilus influenzae
NADH
Na+-NQR is specific to NADH
Klebsiella pneumoniae
NADH
Na+-NQR is specific to NADH
Neisseria gonorrhoeae
NADH
Na+-NQR is specific to NADH
Neisseria meningitidis
NADH
Na+-NQR is specific to NADH
Porphyromonas gingivalis
NADH
Na+-NQR is specific to NADH
Pseudomonas aeruginosa
NADH
Na+-NQR is specific to NADH
Vibrio alginolyticus
NADH
Na+-NQR is specific to NADH
Vibrio cholerae
NADH
Na+-NQR is specific to NADH
Vibrio harveyi
NADH
Na+-NQR is specific to NADH
Yersinia pestis
riboflavin
the enzyme contains one noncovalently bound riboflavin
Azotobacter vinelandii
riboflavin
the enzyme contains one noncovalently bound riboflavin
Haemophilus influenzae
riboflavin
the enzyme contains one noncovalently bound riboflavin
Klebsiella pneumoniae
riboflavin
the enzyme contains one noncovalently bound riboflavin
Neisseria gonorrhoeae
riboflavin
the enzyme contains one noncovalently bound riboflavin
Neisseria meningitidis
riboflavin
the enzyme contains one noncovalently bound riboflavin
Porphyromonas gingivalis
riboflavin
the enzyme contains one noncovalently bound riboflavin
Pseudomonas aeruginosa
riboflavin
the enzyme contains one noncovalently bound riboflavin
Vibrio alginolyticus
riboflavin
the enzyme contains one noncovalently bound riboflavin
Vibrio cholerae
riboflavin
the enzyme contains one noncovalently bound riboflavin
Vibrio harveyi
riboflavin
the enzyme contains one noncovalently bound riboflavin
Yersinia pestis
ubiquinone-8
the enzyme contains one ubiquinone-8
Azotobacter vinelandii
ubiquinone-8
the enzyme contains one ubiquinone-8
Haemophilus influenzae
ubiquinone-8
the enzyme contains one ubiquinone-8
Klebsiella pneumoniae
ubiquinone-8
the enzyme contains one ubiquinone-8
Neisseria gonorrhoeae
ubiquinone-8
the enzyme contains one ubiquinone-8
Neisseria meningitidis
ubiquinone-8
the enzyme contains one ubiquinone-8
Porphyromonas gingivalis
ubiquinone-8
the enzyme contains one ubiquinone-8
Pseudomonas aeruginosa
ubiquinone-8
the enzyme contains one ubiquinone-8
Vibrio alginolyticus
ubiquinone-8
the enzyme contains one ubiquinone-8
Vibrio cholerae
ubiquinone-8
the enzyme contains one ubiquinone-8
Vibrio harveyi
ubiquinone-8
the enzyme contains one ubiquinone-8
Yersinia pestis
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Azotobacter vinelandii
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Haemophilus influenzae
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Klebsiella pneumoniae
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Neisseria gonorrhoeae
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Neisseria meningitidis
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Porphyromonas gingivalis
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Pseudomonas aeruginosa
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Vibrio alginolyticus
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Vibrio cholerae
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Vibrio harveyi
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Yersinia pestis
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Azotobacter vinelandii
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Haemophilus influenzae
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Klebsiella pneumoniae
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Neisseria gonorrhoeae
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Neisseria meningitidis
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Porphyromonas gingivalis
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Pseudomonas aeruginosa
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Vibrio alginolyticus
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Vibrio cholerae
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Vibrio harveyi
FAD
noncovalently bound to the NqrF subunit of Na+-NQR
Yersinia pestis
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Azotobacter vinelandii
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Haemophilus influenzae
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Klebsiella pneumoniae
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Neisseria gonorrhoeae
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Neisseria meningitidis
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Porphyromonas gingivalis
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Pseudomonas aeruginosa
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Vibrio alginolyticus
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Vibrio cholerae
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Vibrio harveyi
FMN
covalently bound to the NqrB and NqrC subunits of Na+-NQR
Yersinia pestis
NADH
Na+-NQR is specific to NADH
Azotobacter vinelandii
NADH
Na+-NQR is specific to NADH
Haemophilus influenzae
NADH
Na+-NQR is specific to NADH
Klebsiella pneumoniae
NADH
Na+-NQR is specific to NADH
Neisseria gonorrhoeae
NADH
Na+-NQR is specific to NADH
Neisseria meningitidis
NADH
Na+-NQR is specific to NADH
Porphyromonas gingivalis
NADH
Na+-NQR is specific to NADH
Pseudomonas aeruginosa
NADH
Na+-NQR is specific to NADH
Vibrio alginolyticus
NADH
Na+-NQR is specific to NADH
Vibrio cholerae
NADH
Na+-NQR is specific to NADH
Vibrio harveyi
NADH
Na+-NQR is specific to NADH
Yersinia pestis
riboflavin
the enzyme contains one noncovalently bound riboflavin
Azotobacter vinelandii
riboflavin
the enzyme contains one noncovalently bound riboflavin
Haemophilus influenzae
riboflavin
the enzyme contains one noncovalently bound riboflavin
Klebsiella pneumoniae
riboflavin
the enzyme contains one noncovalently bound riboflavin
Neisseria gonorrhoeae
riboflavin
the enzyme contains one noncovalently bound riboflavin
Neisseria meningitidis
riboflavin
the enzyme contains one noncovalently bound riboflavin
Porphyromonas gingivalis
riboflavin
the enzyme contains one noncovalently bound riboflavin
Pseudomonas aeruginosa
riboflavin
the enzyme contains one noncovalently bound riboflavin
Vibrio alginolyticus
riboflavin
the enzyme contains one noncovalently bound riboflavin
Vibrio cholerae
riboflavin
the enzyme contains one noncovalently bound riboflavin
Vibrio harveyi
riboflavin
the enzyme contains one noncovalently bound riboflavin
Yersinia pestis
ubiquinone-8
the enzyme contains one ubiquinone-8
Azotobacter vinelandii
ubiquinone-8
the enzyme contains one ubiquinone-8
Haemophilus influenzae
ubiquinone-8
the enzyme contains one ubiquinone-8
Klebsiella pneumoniae
ubiquinone-8
the enzyme contains one ubiquinone-8
Neisseria gonorrhoeae
ubiquinone-8
the enzyme contains one ubiquinone-8
Neisseria meningitidis
ubiquinone-8
the enzyme contains one ubiquinone-8
Porphyromonas gingivalis
ubiquinone-8
the enzyme contains one ubiquinone-8
Pseudomonas aeruginosa
ubiquinone-8
the enzyme contains one ubiquinone-8
Vibrio alginolyticus
ubiquinone-8
the enzyme contains one ubiquinone-8
Vibrio cholerae
ubiquinone-8
the enzyme contains one ubiquinone-8
Vibrio harveyi
ubiquinone-8
the enzyme contains one ubiquinone-8
Yersinia pestis
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Azotobacter vinelandii
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Haemophilus influenzae
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Klebsiella pneumoniae
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Neisseria gonorrhoeae
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Neisseria meningitidis
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Porphyromonas gingivalis
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Pseudomonas aeruginosa
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Vibrio alginolyticus
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Vibrio cholerae
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Vibrio harveyi
[2Fe-2S]-center
part of the NqrF subunit of Na+-NQR
Yersinia pestis
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Haemophilus influenzae
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Klebsiella pneumoniae
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Neisseria gonorrhoeae
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Neisseria meningitidis
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Porphyromonas gingivalis
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Pseudomonas aeruginosa
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Vibrio alginolyticus
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Vibrio harveyi
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Yersinia pestis
2-n-heptyl-4-hydroxyquinoline-N-oxide
-
Vibrio cholerae
Ag+
-
Azotobacter vinelandii
Ag+
-
Haemophilus influenzae
Ag+
-
Neisseria gonorrhoeae
Ag+
-
Neisseria meningitidis
Ag+
-
Porphyromonas gingivalis
Ag+
-
Pseudomonas aeruginosa
Ag+
-
Vibrio cholerae
Ag+
-
Vibrio harveyi
Ag+
-
Yersinia pestis
Ag+
-
Vibrio alginolyticus
Cd2+
-
Azotobacter vinelandii
Cd2+
-
Haemophilus influenzae
Cd2+
-
Klebsiella pneumoniae
Cd2+
-
Neisseria gonorrhoeae
Cd2+
-
Neisseria meningitidis
Cd2+
-
Porphyromonas gingivalis
Cd2+
-
Pseudomonas aeruginosa
Cd2+
-
Vibrio alginolyticus
Cd2+
-
Vibrio cholerae
Cd2+
-
Vibrio harveyi
Cd2+
-
Yersinia pestis
Cu2+
-
Azotobacter vinelandii
Cu2+
-
Haemophilus influenzae
Cu2+
-
Klebsiella pneumoniae
Cu2+
-
Neisseria gonorrhoeae
Cu2+
-
Neisseria meningitidis
Cu2+
-
Porphyromonas gingivalis
Cu2+
-
Pseudomonas aeruginosa
Cu2+
-
Vibrio alginolyticus
Cu2+
-
Vibrio cholerae
Cu2+
-
Vibrio harveyi
Cu2+
-
Yersinia pestis
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Azotobacter vinelandii
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Klebsiella pneumoniae
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Neisseria gonorrhoeae
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Neisseria meningitidis
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Porphyromonas gingivalis
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Pseudomonas aeruginosa
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Vibrio alginolyticus
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Vibrio cholerae
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Vibrio harveyi
korormicin
specifically inhibits Na+-NQR at the level of its interaction with ubiquinone
Yersinia pestis
additional information
Na+-NQR from Azotobacter vinelandii is not sensitive to low 2-n-heptyl-4-hydroxyquinoline-N-oxide concentrations
Azotobacter vinelandii
additional information
korormicin has no effect on the enzyme from Haemophilus influenza
Haemophilus influenzae
additional information
Na+-NQR from Klebsiella pneumoniae is fully resistant to either Ag+ or N-ethylmaleimide
Klebsiella pneumoniae
N-ethylmaleimide
-
Azotobacter vinelandii
N-ethylmaleimide
-
Haemophilus influenzae
N-ethylmaleimide
-
Neisseria gonorrhoeae
N-ethylmaleimide
-
Neisseria meningitidis
N-ethylmaleimide
-
Porphyromonas gingivalis
N-ethylmaleimide
-
Pseudomonas aeruginosa
N-ethylmaleimide
-
Vibrio alginolyticus
N-ethylmaleimide
-
Vibrio cholerae
N-ethylmaleimide
-
Vibrio harveyi
N-ethylmaleimide
-
Yersinia pestis
Pb2+
-
Azotobacter vinelandii
Pb2+
-
Haemophilus influenzae
Pb2+
-
Klebsiella pneumoniae
Pb2+
-
Neisseria gonorrhoeae
Pb2+
-
Neisseria meningitidis
Pb2+
-
Porphyromonas gingivalis
Pb2+
-
Pseudomonas aeruginosa
Pb2+
-
Vibrio alginolyticus
Pb2+
-
Vibrio cholerae
Pb2+
-
Vibrio harveyi
Pb2+
-
Yersinia pestis
Zn2+
-
Azotobacter vinelandii
Zn2+
-
Haemophilus influenzae
Zn2+
-
Klebsiella pneumoniae
Zn2+
-
Neisseria gonorrhoeae
Zn2+
-
Neisseria meningitidis
Zn2+
-
Porphyromonas gingivalis
Zn2+
-
Pseudomonas aeruginosa
Zn2+
-
Vibrio alginolyticus
Zn2+
-
Vibrio cholerae
Zn2+
-
Vibrio harveyi
Zn2+
-
Yersinia pestis
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Azotobacter vinelandii
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Haemophilus influenzae
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Klebsiella pneumoniae
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Neisseria gonorrhoeae
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Neisseria meningitidis
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Porphyromonas gingivalis
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Pseudomonas aeruginosa
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Vibrio alginolyticus
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Vibrio cholerae
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Vibrio harveyi
Na+
specific requirement for sodium ions, even in the absence of sodium ions Na+-NQR is unable to translocate protons
Yersinia pestis
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
21500
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
22700
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
27500
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
45200
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
45400
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
48400
-
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Haemophilus influenzae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio harveyi
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Pseudomonas aeruginosa
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria gonorrhoeae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria meningitidis
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Klebsiella pneumoniae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Azotobacter vinelandii
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Yersinia pestis
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Porphyromonas gingivalis
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio cholerae
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio alginolyticus
-
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
?
additional information
Haemophilus influenzae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Vibrio harveyi
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Pseudomonas aeruginosa
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Neisseria gonorrhoeae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Neisseria meningitidis
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Klebsiella pneumoniae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Azotobacter vinelandii
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Yersinia pestis
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Porphyromonas gingivalis
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Vibrio cholerae
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Vibrio alginolyticus
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
?
-
-
-
additional information
Haemophilus influenzae
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Vibrio harveyi
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Pseudomonas aeruginosa
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Neisseria gonorrhoeae
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Neisseria meningitidis
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Klebsiella pneumoniae
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Azotobacter vinelandii
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Yersinia pestis
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Porphyromonas gingivalis
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Vibrio cholerae
Na+-NQR does not oxidize NADPH
?
-
-
-
additional information
Vibrio alginolyticus
Na+-NQR does not oxidize NADPH
?
-
-
-
NADH + H+ + ubiquinone + 2 Na+/in
Haemophilus influenzae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Vibrio harveyi
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Pseudomonas aeruginosa
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Neisseria gonorrhoeae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Neisseria meningitidis
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Klebsiella pneumoniae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Azotobacter vinelandii
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Yersinia pestis
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Porphyromonas gingivalis
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Vibrio cholerae
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
Vibrio alginolyticus
-
NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Haemophilus influenzae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio harveyi
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Pseudomonas aeruginosa
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria gonorrhoeae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Neisseria meningitidis
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Klebsiella pneumoniae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Azotobacter vinelandii
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Yersinia pestis
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Porphyromonas gingivalis
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio cholerae
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
Vibrio alginolyticus
-
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Haemophilus influenzae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio harveyi
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Pseudomonas aeruginosa
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria gonorrhoeae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria meningitidis
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Klebsiella pneumoniae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Azotobacter vinelandii
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Yersinia pestis
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Porphyromonas gingivalis
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio cholerae
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
deamino-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio alginolyticus
deamino-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Haemophilus influenzae
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Vibrio harveyi
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Pseudomonas aeruginosa
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Neisseria gonorrhoeae
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Neisseria meningitidis
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Klebsiella pneumoniae
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Azotobacter vinelandii
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Yersinia pestis
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Porphyromonas gingivalis
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Vibrio cholerae
?
-
-
-
-
additional information
in addition to the quinone reductase reaction, the isolated enzyme can also catalyze the so-called NADH-dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexaammineruthenium (III), ferricyanide, etc.)
711293
Vibrio alginolyticus
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Haemophilus influenzae
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Vibrio harveyi
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Pseudomonas aeruginosa
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Neisseria gonorrhoeae
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Neisseria meningitidis
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Klebsiella pneumoniae
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Azotobacter vinelandii
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Yersinia pestis
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Porphyromonas gingivalis
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Vibrio cholerae
?
-
-
-
-
additional information
Na+-NQR does not oxidize NADPH
711293
Vibrio alginolyticus
?
-
-
-
-
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Haemophilus influenzae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio harveyi
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Pseudomonas aeruginosa
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria gonorrhoeae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria meningitidis
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Klebsiella pneumoniae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Azotobacter vinelandii
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Yersinia pestis
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Porphyromonas gingivalis
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio cholerae
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio alginolyticus
NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Haemophilus influenzae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio harveyi
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Pseudomonas aeruginosa
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria gonorrhoeae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Neisseria meningitidis
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Klebsiella pneumoniae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Azotobacter vinelandii
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Yersinia pestis
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Porphyromonas gingivalis
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio cholerae
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
thio-NADH + H+ + ubiquinone + 2 Na+/in
-
711293
Vibrio alginolyticus
thio-NAD+ + ubiquinol + 2 Na+/out
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
heterohexamer
1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200, calculated from amino acid sequence
Vibrio harveyi
Other publictions for EC 7.2.1.1
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
742030
Toulouse
Strong pH dependence of coupl ...
Vibrio cholerae O1, Vibrio cholerae O1 ATCC 39315
Biol. Chem.
398
251-260
2017
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742911
Ito
-
Identification of the binding ...
Vibrio cholerae O1, Vibrio cholerae O1 ATCC 39315
J. Biol. Chem.
292
7727-7742
2017
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741981
Belevich
Identification of the couplin ...
Vibrio harveyi
Biochim. Biophys. Acta
1857
141-149
2016
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741985
Vorburger
Role of the Na+-translocating ...
Vibrio cholerae O1, Vibrio cholerae O1 ATCC 39541
Biochim. Biophys. Acta
1857
473-482
2016
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1
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742791
Muras
The Na+-translocating NADHqui ...
Vibrio cholerae O1, Vibrio cholerae O1 ATCC 39315
J. Bacteriol.
198
2307-2317
2016
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1
1
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732678
Borshchevskiy
Structural and functional inve ...
Vibrio harveyi, Vibrio harveyi CAIM 1792
PLoS ONE
10
e0118548
2015
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742029
Steuber
The structure of Na+-transloc ...
Vibrio cholerae O1, Vibrio cholerae O1 ATCC 39315
Biol. Chem.
396
1015-1030
2015
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732791
Minato
Roles of the sodium-translocat ...
Vibrio cholerae
PLoS ONE
9
e97083
2014
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1
1
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741533
Vohl
-
Crystallization and prelimina ...
Vibrio cholerae O1, Vibrio cholerae O1 ATCC 39541
Acta Crystallogr. Sect. F
70
987-992
2014
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1
1
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741955
Bertsova
Localization-controlled speci ...
Klebsiella pneumoniae
Biochim. Biophys. Acta
1837
1122-1129
2014
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1
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742860
Strickland
The conformational changes in ...
Vibrio cholerae O1, Vibrio cholerae O1 ATCC 39541
J. Biol. Chem.
289
23723-23733
2014
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743239
Minato
-
Inhibition of the sodium-tran ...
Vibrio cholerae O1, Vibrio cholerae O1 ATCC 39541
Microb. Pathog.
66
36-39
2014
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743346
Steuber
Structure of the V. cholerae ...
Vibrio cholerae O1, Vibrio cholerae O1 ATCC 39315
Nature
516
62-67
2014
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1
1
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8
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725538
Nedielkov
NMR reveals double occupancy o ...
Vibrio cholerae
J. Biol. Chem.
288
30597-30606
2013
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1
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3
3
3
1
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1
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1
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3
1
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1
1
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1
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2
2
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725539
Shea
Aspartic acid 397 in subunit B ...
Vibrio cholerae, Vibrio cholerae ATCC 39541
J. Biol. Chem.
288
31241-31249
2013
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1
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7
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1
12
1
3
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1
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8
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1
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6
1
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56
1
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4
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1
4
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14
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1
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12
1
3
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1
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1
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6
1
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56
1
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2
2
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741884
Neehaul
-
Infrared spectroscopic eviden ...
Vibrio cholerae O1, Vibrio cholerae O1 ATCC 39541
Biochemistry
52
3085-3093
2013
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1
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1
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3
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3
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742842
Bertsova
Alternative pyrimidine biosyn ...
Klebsiella pneumoniae 204, Klebsiella pneumoniae, Vibrio harveyi, Vibrio harveyi R3
J. Biol. Chem.
288
14276-14286
2013
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2
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2
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9
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2
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12
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12
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4
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4
2
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3
3
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725481
Juarez
The role of glycine residues 1 ...
Vibrio cholerae, Vibrio cholerae ATCC 39541
J. Biol. Chem.
287
25678-25685
2012
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5
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1
11
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1
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8
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4
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10
1
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4
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4
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10
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2
7
11
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1
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4
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10
1
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3
3
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1
1
724251
Fadeeva
Cys377 residue in NqrF subunit ...
Vibrio harveyi
Biochemistry (Moscow)
76
186-195
2011
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1
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8
2
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1
1
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1
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1
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725433
Juarez
The role and specificity of th ...
Vibrio cholerae
J. Biol. Chem.
286
26383-26390
2011
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1
1
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725448
Casutt
Localization of ubiquinone-8 i ...
Vibrio cholerae
J. Biol. Chem.
286
40075-40082
2011
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1
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1
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1
1
1
1
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4
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1
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3
3
1
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1
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1
3
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1
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1
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3
3
1
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1
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1
1
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710746
Casutt
Crystallization of the Na+-tra ...
Vibrio cholerae
Acta Crystallogr. Sect. F
66
1677-1679
2010
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1
1
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3
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1
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3
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1
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1
1
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6
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6
1
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3
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1
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1
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1
1
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711293
Verkhovsky
Sodium-translocating NADH:quin ...
Azotobacter vinelandii, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Neisseria meningitidis, Porphyromonas gingivalis, Pseudomonas aeruginosa, Vibrio alginolyticus, Vibrio cholerae, Vibrio harveyi, Yersinia pestis
Biochim. Biophys. Acta
1797
738-746
2010
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-
87
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11
6
55
-
13
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55
1
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-
66
-
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66
-
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87
-
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11
6
55
-
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55
1
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713414
Juarez
Energy transducing redox steps ...
Vibrio cholerae
Proc. Natl. Acad. Sci. USA
107
12505-12510
2010
-
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5
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1
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5
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5
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1
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1
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1
1
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725402
Casutt
Localization and function of t ...
Vibrio cholerae
J. Biol. Chem.
285
27088-27099
2010
-
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1
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1
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1
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5
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1
1
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3
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1
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1
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3
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1
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4
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1
4
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1
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1
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5
-
1
1
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1
1
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3
-
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1
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1
1
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696344
Bogachev
Redox properties of the prosth ...
Vibrio harveyi
Biochemistry
48
6291-6298
2009
-
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1
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3
-
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1
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1
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696345
Bogachev
Redox properties of the prosth ...
Vibrio harveyi
Biochemistry
48
6299-6304
2009
-
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1
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3
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3
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1
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3
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1
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6
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1
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1
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1
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1
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696157
Fadeeva
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696386
Tao
Oxidant-induced formation of a ...
Vibrio cholerae
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2
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1
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4
2
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1
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697973
Fadeeva
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3
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3
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3
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2
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3
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5
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1
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2
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2
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1
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1
1
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1
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6
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2
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1
1
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2
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2
-
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671141
Tao
Crystallization of the NADH-ox ...
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Acta Crystallogr. Sect. F
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1
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1
1
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1
1
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3
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3
1
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1
1
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1
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1
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671351
Brandt
Energy converting NADH:quinone ...
Arabidopsis thaliana, Bos taurus, Caenorhabditis elegans, Chlamydomonas reinhardtii, Drosophila melanogaster, Escherichia coli, Homo sapiens, Klebsiella pneumoniae, Mus musculus, Neurospora crassa, Oryza sativa, Paracoccus denitrificans, Rhodomonas salina, Thermus thermophilus, Yarrowia lipolytica
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45
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93
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15
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42
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Bogachev
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1
2
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1
1
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1
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1
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1
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2
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1
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672293
Bogachev
Na(+)-translocating NADH:quino ...
Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Neisseria meningitidis, Porphyromonas gingivalis, Pseudomonas aeruginosa, Salinivibrio costicola, Shewanella putrefaciens, Vibrio alginolyticus, Vibrio harveyi, Yersinia pestis
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33
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1
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6
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1
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1
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1
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711269
Bogachev
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Barquera
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Vibrio cholerae
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658163
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